Drug Intelligence Infrastructure

Drug intelligence infrastructure for healthcare analytics

TwinFyRx transforms fragmented drug reference data into a unified platform for analytics and product development. Normalize NDCs. Navigate the RxNorm hierarchy. Map drugs to conditions. Analyze therapy patterns and drug economics — all through a modern API and SDK.

Core Capabilities

Everything you need to work with drug data.

From NDC normalization through diagnosis inference, therapy classification, and pricing benchmarks — structured for claims pipelines, data warehouses, and analytics platforms.

Drug Identity

Resolve messy NDC data into clean clinical drug concepts.

  • —NDC normalization
  • —RxNorm hierarchy reconstruction
  • —Pack size normalization
  • —Clinical drug form resolution
Clinical Context

Understand what drugs actually treat.

  • —ICD-10 condition associations
  • —Therapy classifications
  • —Maintenance therapy flags
  • —Route and treatment pattern enrichment
Drug Economics

Analyze therapy cost and utilization patterns.

  • —NADAC pricing
  • —ASP pricing
  • —Defined daily dose normalization
  • —Pack size economics
Claims Intelligence

Derive insights directly from pharmacy claims.

  • —Diagnosis suspecting
  • —Therapy pattern detection
  • —Treatment pathway signals

Developer Experience

Designed for modern healthcare data teams.

Not spreadsheets.

example.py
from twinfyrx import Client client = Client() drug = client.drugs.get_by_ndc("00093-7424") drug.clinical_drug # Lisinopril 10 MG Oral Tablet drug.therapy_class # C09AA — ACE inhibitors drug.conditions # [{I10: 61%}, {I50.9: 22%}] drug.pricing.nadac # $0.0312 per unit

Platform Features

  • REST API
  • Python SDK
  • SQL SDK
  • Structured datasets
  • Versioned releases
  • Interactive documentation
  • Sandbox environments

What Teams Build

What teams build with TwinFyRx

From diagnosis suspecting to drug cost analysis, TwinFyRx provides the intelligence layer that powers real healthcare analytics products.

Diagnosis Suspecting

Identify likely chronic conditions from pharmacy claims. Used by risk adjustment analytics platforms, population health systems, and value-based care organizations.

Drug Economics

Understand the real cost of therapy. Used by value-based care analytics, pharmacy cost strategy teams, and clinical utilization analysis.

Clinical Drug Intelligence

Connect drug utilization with disease patterns. Used by digital health platforms, healthcare analytics startups, and payer analytics teams.

Featured Guide

How to map drugs to indications

Drug-to-disease mapping is the foundation of diagnosis suspecting and drug intelligence, and it can’t be sourced from open data alone. See how we approach it, with worked examples and an explorer you can try.

  • Why open sources like NLM MED-RT can't answer “what is this drug actually prescribed for?”
  • How indications are modeled the way clinicians think, then mapped to ICD-10
  • How per-drug shares are validated against AHRQ MEPS
Read the guide

Watch the guide in under five minutes.

Sandbox

Try TwinFyRx in the Sandbox

Explore the platform using synthetic pharmacy claims and real drug reference data. Query any drug and browse every enrichment layer — visual cards or raw JSON. No setup required.

Try the Drug Economics Lab — see how raw claims become therapy cost insights →
Try:
twinfyrx-api — sandbox v1
// Enter a drug name or RxNorm CUI above // and click Run Query to see live data. // // Examples: pembrolizumab, semaglutide, adalimumab

Who We Are

Built by healthcare data engineers

TwinFyRx was created by engineers who have spent years building analytics infrastructure for healthcare organizations. The platform reflects real-world data challenges faced by healthcare analytics teams.

Value-based care organizationsPopulation health platformsPayer analytics systemsHealthcare data integration platforms

Plans

One dataset. Priced for how you use it.

Every plan includes the full TwinFyRx dataset. Plans differ in refresh cadence, delivery, and usage rights.

Developer

Free

work email required


Explore the full schema and build against real data before you commit.

  • ✓Full dataset, monthly snapshot
  • ✓REST API with a developer key
  • ✓Documentation and sample data
  • ✓Evaluation and prototyping only

Professional

Contact sales

monthly or annual license


For analytics and product teams putting TwinFyRx data into production.

  • ✓Full dataset, refreshed weekly
  • ✓REST API with production limits
  • ✓Bulk delivery via Parquet or MotherDuck share
  • ✓Production use across your organization
  • ✓Embed in your own product
  • ✓Email support

Enterprise

Contact sales

annual license


Priced by organization size and deployment model.

  • ✓Everything in Professional
  • ✓Redistribution and OEM rights
  • ✓Multiple products, affiliates, or subsidiaries
  • ✓Delivery SLA and higher API limits
  • ✓Security review, MSA, and procurement support
  • ✓Named contact

Pricing for Professional and Enterprise is set per customer. Embedding means TwinFyRx data powers features inside your product; distributing the data itself requires Enterprise.

Included in every plan

Drug Foundation

Clean drug identity and economics on open standard IDs.

  • —RxNorm drug hierarchy
  • —NDC crosswalk (NDC-11, NDC-10, NDC-9)
  • —ATC classes, ingredients, dose forms
  • —Therapy pattern and benefit channel
  • —NADAC and ASP pricing with history
  • —Pack size and defined daily dose
  • —Drug economics marts

Pharmacy Intelligence

What drugs treat, how they're covered, and how claims route.

  • —Utilization-weighted ICD-10 indications
  • —Part D formulary signals and access friction
  • —PBM inference and BIN/PCN routing
  • —Pharmacy directory
  • —Canada DIN to RxNorm crosswalk

Risk & Suspecting

Diagnosis signals from pharmacy claims alone.

  • —Drug → HCC suspects with confidence tiers
  • —CMS-HCC and RxHCC mappings
  • —Suspecting SDK with synthetic claims

Start exploring TwinFyRx

Access the sandbox or speak with us about integrating TwinFyRx into your analytics platform.

Launch Sandbox